Closed Loop Control in Continuous Drug Substance Manufacturing

Time: 12:00 pm
day: Day One Track A AM


• The goal: optimal operation in the face of disturbances

without manual attendance

• Use of PAT as well as online sampling and non-PAT

techniques (LC) in closed loop system

• Robustness is key: ensuring your closed loop control setup

is robust to measurement errors/artifacts and stable

across all visitable scenarios