Workshop A 8.00 - 11.00
Biologics Bootcamp: How to Implement Continuous Processing in Biologics
101 bootcamp on how to implement continuous processing in biologics in a ‘right first-time approach’. Take part in a series of presentations, panel, and audience discussions on the following topics.
• Introduction to continuous processing in biologics: State of play for the industry in upstream, downstream, and end-to-end CM
• Downstream processing deep dive and discussion on application in new modalities
• Analytical technologies and control strategy in bioprocessing
• Scaling up to GMP and challenges with capability building
Workshop B 11.30 - 14.30
Digital Twins & Modelling for Advanced Process Control
The Digital Twin has demonstrated its benefit at different levels and various applications for reducing costs, improving quality, and shortening the time-to-market. Similar to the other chemical processing industries, the digital twin approach can benefit the continuous (and batch) manufacturing in the pharmaceutical industry. The different applications widely span from R&D, to equipment sizing, process development and integration, process control, manufacturing, and CMC and regulatory purpose.
In this workshop, different tools and approaches will be discussed with case studies for continuous drug substance, drug product, and biologics for rapid and efficient commercialization. We will practice different levels of digital twin development and applications from fundamental knowledge development, parameter estimation, model development and deployment,
process control and hybrid models.
Workshop C 15.00 - 18.00
Continuous Processing - Beyond Tubular Reactor
Slurries handling is a frequent challenge for continuous manufacturing within the pharmaceutical sector – but one that has been many times conquered in other industries. The absence of low throughput reactors which can handle slurries under flow conditions has caused many challenges for CM. In this workshop, we take a cross-section of pharma, agrochemical, oil and other industries to understand what techniques and tools can be leveraged for inspiration and applied to the highly regulated and smaller volume industry of pharmaceutical manufacturing. Hear from a range of experts as we evaluate the current bottlenecks for CM and what’s next beyond tubular reactors.