Jan 29 – Jan 31, 2019
Boston, MA

Workshop A
Tuesday January 30, 2018

08.00 - 11.00
Going Continuous for Sure, but Why & How?

Despite the current infatuation for continuous manufacturing technologies, some interrogations remain about the real gain brought when turning continuous.

This workshop will enable you to thoroughly compare batch and continuous processes from a chemical engineering perspective, and see in which circumstances and why CM can be a real game changer. Through various case studies we will investigate scenarios where the choice between batch and continuous is not as easy as it may seem. Moreover, this workshop will demonstrate how process modeling can be used as an efficient tool for a smooth implementation of CM. Modeling can really be a powerful asset to understand, compare and design your processes.

This workshop will help you:

  • Rationalize your decision when investigating continuous technology
  • Make sound choices and investigate various scenarios with the help of process modeling
  • Gain confidence when implementing a new continuous process

Workshop Leaders: Roger-Marc Nicoud, Founder & CEO, Ypso-FactoDavid Pfister, Project Manager, Ypso-Facto

Workshop B
Tuesday January 30, 2018

11.30 - 14.30
Do’s & Dont’s in Continuous Manufacturing Biotech Facility Design

The advantages of continuous bioprocessing include increased productivity, flexibility of operations and decreased facility footprint. That being said, a detailed thought process needs to be incorporated during facility design and ancillary support services.

This workshop will provide you with a step-by-step guide of how to optimize facility suitable for continuous bioprocessing in a cost-efficient way.

Key takeaways:

  • Benefit from hands-on experience with the design and operation of CM facilities
  • Explore a holistic approach to establishing a CM facility from design to operations, and other logistical considerations
  • Gain insight into the regulatory expectations
  • Address real time process control, strategy and requirements for successful CM operations

Workshop Leaders: Morten Munk, Global Technology Partner, NNEJeffery Odum, Global Technology Partner, Strategic Manufacturing Concept Group, NNE Niels Guldager, Global Technology Partner, NNE, Kim Vincentz Andersen, Specialist, Active Products, Biotech, NNE, Valerie Amsler, Process Engineer, NNE

Workshop C
Tuesday January 30, 2018

15.00 - 18.00
Realizing Robust Process Control for Continuous Manufacturing

Traditional batch processing consists of distinct unit operations with sufficient time for verifying forward processing conditions based on critical quality attributes before progressing to the next unit operations. In a Continuous Manufacturing (CM) process, quality attributes must be verified real time to prevent exposing downstream units with out-of-specification material. While batch processing can usually be scaled by discrete steps (batches per year), CM provides the opportunity to scale throughput by modulating flow rates through the system and provides additional degrees of freedom in operational flexibility. A tightly integrated Process Control System and Real Time Dynamic Model provides the ability to manage the complexity of interlinked material transport, reaction rates, and equilibrium conditions. A well designed control and real time modeling strategy can enable process options which are otherwise not possible by expanding design space constraints and improving process understanding.

This workshop will enable you to:

  • Understand the components of an integrated control strategy and real time modeling and how they interact during each phase of the project lifecycle, from process design through scale up, validation, and operation
  • Assess the considerations and benefits of integrating control strategy design and real time modeling with the design of the overall process
  • Understand what to include and what to ask when preparing a bid package or project plan for a CM process with a tightly integrated control and modeling strategy

Workshop Leader: Terry Seanard, Principal Engineer, New England Controls, Inc.